The band From Autumn to Ashes references Darger in the song “Placentapede”.

Indie rock band …And You Will Know Us by the Trail of Dead have a song titled “Segue: In the Realms of the Unreal” on their 2006 album So Divided.

Neil Gaiman also references Darger’s work in a story contained in a Sandman collection, Endless Nights. In the episode called Going Inside, Delirium is saved from having gone too deep inside her own mind by five mentally challenged people and her guardian dog. One of the characters, an old man, is writing and illustrating a mammoth project that resembles Darger’s work very closely in the loneliness of his own house. However, the reference has to be considered inspirational rather than factual, as fictional details, such as the man punishing himself for not having written enough pages per day, are installed into the character’s story.

Philadelphia duo The Vivian Girls Experience take their name and image from Darger’s work.

Indie band Tilly and the Wall have a song titled Lost Girls which was inspired by Darger’s work.

Artist/Activist Paul Chan created an artwork in 2003 entitled “Happiness (Finally) After 35,000 Years of Civilization–After Henry Darger and Charles Fourier”

The band formerly known as Mazarin (now called Black Stoltzfus) has a song called “Henry Darger”.

Chicago theatre company Dog And Pony created and produced an original work, entitled “As Told By The Vivian Girls,” based on In The Realms Of The Unreal, and performed it at Theatre On The Lake, a theatre in the same neighborhood as Darger’s Chicago studio apartment.